Rare Disease Day is the globally-coordinated movement on rare diseases.
February 28, 2025 is World Rare Disease Day. Help raise awareness for mast cell diseases and related conditions, while encouraging research.
Mast cells are "master regulators" of the immune system. They come from bone marrow and go into all tissues of the body. Some diseases, such as mastocytosis, derive from an increased number of mast cells. Others, such as Mast Cell Activation Syndrome (MCAS), are the result of the activation of mast cells.
"What are Mast Cell Disorders and Mastocytosis?"
Dr. M. Castells, American Academy of Allergy Asthma & Immunology, Video, 7/28/16
Some diseases, such as mastocytosis, derive from an increased number of mast cells. Others, such as Mast Cell Activation Syndrome (MCAS), are the result of the activation of mast cells. But did you know that many other diseases and disorders have been found to involve mast cell activation, including asthma, chronic fatigue syndrome, coronary hypersensitivity syndrome, eczema, fibromyalgia, idiopathic anaphylaxis, irritable bowel syndrome, multiple chemical sensitivity syndrome, neuroinflammation, postural orthostatic tachycardia syndrome (POTS), psoriasis, and even autism. [show/hide more]
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